https://www.gphjournal.org/index.php/as/issue/feed 2025-10-14T11:09:44+00:00 Dr. EKEKE, JOHN NDUBUEZE drekekejohn@gmail.com Open Journal Systems <p style="font-family: 'Segoe UI', sans-serif; font-size: 16px; color: #333;"><strong>GPH-International Journal of Applied Science&nbsp;(e-ISSN&nbsp;<a href="https://portal.issn.org/resource/ISSN/3050-9653" target="_blank" rel="noopener">3050-9653</a>)</strong> is a peer-reviewed, open-access journal dedicated to promoting the practical application of scientific discoveries across diverse disciplines. The journal publishes original research, comprehensive reviews, and case studies in areas such as engineering, technology, environmental science, biotechnology, and more. It serves as a global platform for researchers, practitioners, and innovators to share cutting-edge solutions, address real-world challenges, and drive progress in applied science.</p> https://www.gphjournal.org/index.php/as/article/view/2119 2025-10-09T07:05:38+00:00 Carlos Alberto Anjoletto Macedo noreplygphjournals@gmail.com Murillo de Oliveira Dias noreplygphjournals@gmail.com

<p>This article addresses the challenges of negotiating and resolving conflicts at work in a high-pressure logistics consulting environment in Brazil. An intern working on a challenging project for a major shoe company disagrees with his project manager about how to balance work and life and what the job should entail. As the stakes rise, the intern must find a solution by weighing various options and interests. This study provides a comprehensive analysis of the negotiation dynamics, highlighting the challenges of reconciling conflicting priorities and expectations in a rapidly evolving industry. This study enhances our understanding of how to handle conflict and negotiate within organizations effectively.</p>

2025-10-09T07:05:38+00:00 ##submission.copyrightStatement## https://www.gphjournal.org/index.php/as/article/view/2126 2025-10-14T11:09:44+00:00 Saronee F. noreplygphjournals@gmail.com Okari K. noreplygphjournals@gmail.com Peter D. A. noreplygphjournals@gmail.com Nwikue G. noreplygphjournals@gmail.com Ante I. A. noreplygphjournals@gmail.com Buduburusi R. noreplygphjournals@gmail.com

<p>Phytosterols&nbsp;are like&nbsp;<a href="https://en.wikipedia.org/wiki/Cholesterol">cholesterol</a> and maintain structural components of plant cell membrane. The present study aims to investigate the glycemic and biochemical effects of phytosterol using Wistar rats as experimental models. Fifteen (15) female Wistar rats were divided randomly into three (3) groups, each consisting of five (5) rats. Group I served as control and rats in this group were administered distilled water. Groups II and III served as the treatment groups and received 1000 and 2000mg/kg body weight of phytosterol respectively. Phytosterol was orally administered daily for twenty-eight (28) days in the morning hours (8-9am daily). During the study, serum blood glucose level was determined twice via tail vein puncture technique: firstly, before the administration of phytosterol (pre-treatment blood glucose: Day 0); secondly, at the end of the study (post-treatment blood glucose: Day 29). At the end of treatment, (Day 29), blood samples were collected via direct cardiac puncture and stored in lithium heparin tubes for analysis of biochemical indices. Findings from this study indicate that phytosterol treatment resulted in a significant and dose dependent decrease in blood glucose, total cholesterol, triglyceride, low-density lipoprotein, and malondialdehyde levels in the experimental groups relative to control (p &lt; 0.05). Conversely, a significant and dose dependent increase was observed in the mean animal weight, high-density lipoprotein, glutathione, superoxide dismutase and catalase concentrations among the experimental rats compared to control (p&lt;0.05). Evidence from this study suggests that phytosterol treatment lowers blood glucose level, decrease lipid profile and basal oxidative stress markers by decreasing glycemic indices, cardiovascular risks and oxidative disruptions. This effect is probably achieved via beta cell stimulation and decreased reactive oxygen species radicals.</p>

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